Sohoni served as a law clerk to the Honorable Judith W. Rogers of the U.S. Court of Appeals for the District of Columbia Circuit. She practiced law at Jenner & Block LLP in New York and Washington, DC and was an acting assistant professor of lawyering at New York University School of Law. She joined the USD School of Law faculty in 2013. Before attending law school, Sohoni spent two years as a correspondent for The Economist magazine in New York and in London. In 2018, Sohoni was a visiting professor at the University of Pennsylvania Law School and at the Harvard Law School. Professor Sohoni teaches and writes in the areas of civil procedure, administrative law, federal courts, legislation and health law.